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Comparative Exploration of Hydrogen Sulfide and Water Trans-Membrane Free Energy Surfaces via Orthogonal Space Tempering Free Energy Sampling

Hydrogen sulfide (H(2)S), a commonly known toxic gas compound, possesses unique chemical features that allow this small solute molecule to quickly diffuse through cell membranes. Taking advantage of the recent orthogonal space tempering (OST) method, we comparatively mapped the trans-membrane (POPC)...

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Detalles Bibliográficos
Publicado en:J Comput Chem
Main Authors: Lv, Chao, Aitchison, Erick W., Wu, Dongsheng, Zheng, Lianqing, Cheng, Xiaolin, Yang, Wei
Formato: Artigo
Idioma:Inglês
Publicado: 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4959446/
https://ncbi.nlm.nih.gov/pubmed/26119423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcc.23982
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