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Effects of aging and dietary restriction on ubiquitination, sumoylation, and the proteasome in the spleen

In the present study we demonstrate for the first time that aging increases the levels of ubiquitinated protein in the spleen, and that dietary restriction (DR) significantly reduces these age-related increases in ubiquitinated protein. Sumoylated protein, proteasome subunits, and a protein essentia...

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Publicat a:FEBS Lett
Autors principals: Zhang, Le, Li, Feng, Dimayuga, Edgardo, Craddock, Jeffrey, Keller, Jeffrey N.
Format: Artigo
Idioma:Inglês
Publicat: 2007
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4959423/
https://ncbi.nlm.nih.gov/pubmed/17991438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2007.10.054
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