Phase I study to evaluate toxicity and feasibility of intratumoral injection of α-gal glycolipids in patients with advanced melanoma

Effective uptake of tumor cell-derived antigens by antigen-presenting cells is achieved pre-clinically by in situ labeling of tumor with α-gal glycolipids that bind the naturally occurring anti-Gal antibody. We evaluated toxicity and feasibility of intratumoral injections of α-gal glycolipids as an...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Cancer Immunol Immunother
Κύριοι συγγραφείς: Albertini, Mark R., Ranheim, Erik A., Zuleger, Cindy L., Sondel, Paul M., Hank, Jacquelyn A., Bridges, Alan, Newton, Michael A., McFarland, Thomas, Collins, Jennifer, Clements, Erin, Henry, Mary Beth, Neuman, Heather B., Weber, Sharon, Whalen, Giles, Galili, Uri
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Springer Berlin Heidelberg 2016
Θέματα:
Original Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4958541/
https://ncbi.nlm.nih.gov/pubmed/27207605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-016-1846-1
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