Phase I study to evaluate toxicity and feasibility of intratumoral injection of α-gal glycolipids in patients with advanced melanoma

Effective uptake of tumor cell-derived antigens by antigen-presenting cells is achieved pre-clinically by in situ labeling of tumor with α-gal glycolipids that bind the naturally occurring anti-Gal antibody. We evaluated toxicity and feasibility of intratumoral injections of α-gal glycolipids as an...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Cancer Immunol Immunother
Autori principali: Albertini, Mark R., Ranheim, Erik A., Zuleger, Cindy L., Sondel, Paul M., Hank, Jacquelyn A., Bridges, Alan, Newton, Michael A., McFarland, Thomas, Collins, Jennifer, Clements, Erin, Henry, Mary Beth, Neuman, Heather B., Weber, Sharon, Whalen, Giles, Galili, Uri
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer Berlin Heidelberg 2016
Soggetti:
Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4958541/
https://ncbi.nlm.nih.gov/pubmed/27207605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-016-1846-1
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi