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Adoptive transfer of osteoclast-expanded natural killer cells for immunotherapy targeting cancer stem-like cells in humanized mice

Based on data obtained from oral, pancreatic and lung cancers, glioblastoma, and melanoma, we have established that natural killer (NK) cells target cancer stem-like cells (CSCs). CSCs displaying low MHC class I, CD54, and PD-L1 are killed by cytotoxic NK cells and are differentiated by split anergi...

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Detalhes bibliográficos
Publicado no:Cancer Immunol Immunother
Main Authors: Kozlowska, Anna K., Kaur, Kawaljit, Topchyan, Paytsar, Jewett, Anahid
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4958457/
https://ncbi.nlm.nih.gov/pubmed/27034236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-016-1822-9
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