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SOX2 is sequentially required for progenitor proliferation and lineage specification in the developing pituitary
Sox2 mutations are associated with pituitary hormone deficiencies and the protein is required for pituitary progenitor proliferation, but its function has not been well characterized in this context. SOX2 is known to activate expression of Six6, encoding a homeodomain transcription factor, in the ve...
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| Veröffentlicht in: | Development |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Company of Biologists Ltd
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4958329/ https://ncbi.nlm.nih.gov/pubmed/27226320 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.137984 |
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