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Eravacycline Pharmacokinetics and Challenges in Defining Humanized Exposure In Vivo
We assessed the pharmacokinetic profile of eravacycline, a novel antibiotic of the tetracycline class, and determined the dose in an immunocompetent murine thigh infection model that would provide free-drug exposure similar to that observed in humans after the administration of 1 mg/kg intravenously...
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| Publicado no: | Antimicrob Agents Chemother |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4958217/ https://ncbi.nlm.nih.gov/pubmed/27353264 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00240-16 |
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