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Antimalarial Benzoxaboroles Target Plasmodium falciparum Leucyl-tRNA Synthetase

There is a need for new antimalarials, ideally with novel mechanisms of action. Benzoxaboroles have been shown to be active against bacteria, fungi, and trypanosomes. Therefore, we investigated the antimalarial activity and mechanism of action of 3-aminomethyl benzoxaboroles against Plasmodium falci...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Sonoiki, Ebere, Palencia, Andres, Guo, Denghui, Ahyong, Vida, Dong, Chen, Li, Xianfeng, Hernandez, Vincent S., Zhang, Yong-Kang, Choi, Wai, Gut, Jiri, Legac, Jennifer, Cooper, Roland, Alley, M. R. K., Freund, Yvonne R., DeRisi, Joseph, Cusack, Stephen, Rosenthal, Philip J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4958189/
https://ncbi.nlm.nih.gov/pubmed/27270277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00820-16
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