Oridonin inhibits pancreatic cancer cell migration and epithelial-mesenchymal transition by suppressing Wnt/β-catenin signaling pathway

BACKGROUND: Oridonin (ORI) can inhibit proliferation and migration in various types of cancer cell lines. However, the exact mechanism remains unclear. We investigated the migration inhibitory effect of ORI on human pancreatic cancer SW1990 cells and dissected the possible molecular mechanism(s). ME...

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Veröffentlicht in:Cancer Cell Int
Hauptverfasser: Liu, Qian-Qian, Chen, Ke, Ye, Qiao, Jiang, Xiao-Hua, Sun, Yun-Wei
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2016
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Primary Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4957915/
https://ncbi.nlm.nih.gov/pubmed/27453691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-016-0336-z
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