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Oridonin inhibits pancreatic cancer cell migration and epithelial-mesenchymal transition by suppressing Wnt/β-catenin signaling pathway

BACKGROUND: Oridonin (ORI) can inhibit proliferation and migration in various types of cancer cell lines. However, the exact mechanism remains unclear. We investigated the migration inhibitory effect of ORI on human pancreatic cancer SW1990 cells and dissected the possible molecular mechanism(s). ME...

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Publicat a:Cancer Cell Int
Autors principals: Liu, Qian-Qian, Chen, Ke, Ye, Qiao, Jiang, Xiao-Hua, Sun, Yun-Wei
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4957915/
https://ncbi.nlm.nih.gov/pubmed/27453691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-016-0336-z
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