Oridonin inhibits pancreatic cancer cell migration and epithelial-mesenchymal transition by suppressing Wnt/β-catenin signaling pathway

BACKGROUND: Oridonin (ORI) can inhibit proliferation and migration in various types of cancer cell lines. However, the exact mechanism remains unclear. We investigated the migration inhibitory effect of ORI on human pancreatic cancer SW1990 cells and dissected the possible molecular mechanism(s). ME...

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Vydáno v:Cancer Cell Int
Hlavní autoři: Liu, Qian-Qian, Chen, Ke, Ye, Qiao, Jiang, Xiao-Hua, Sun, Yun-Wei
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2016
Témata:
Primary Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4957915/
https://ncbi.nlm.nih.gov/pubmed/27453691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-016-0336-z
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