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Neutrophils from patients with SAPHO syndrome show no signs of aberrant NADPH oxidase-dependent production of intracellular reactive oxygen species

Objective. We aimed to investigate if aberrant intracellular production of NADPH oxidase-derived reactive oxygen species (ROS) in neutrophils is a disease mechanism in the autoinflammatory disease SAPHO syndrome, characterized by synovitis, acne, pustulosis, hyperostosis and osteitis, as has previou...

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Publicat a:Rheumatology (Oxford)
Autors principals: Wekell, Per, Björnsdottir, Halla, Björkman, Lena, Sundqvist, Martina, Christenson, Karin, Osla, Veronica, Berg, Stefan, Fasth, Anders, Welin, Amanda, Bylund, Johan, Karlsson, Anna
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4957673/
https://ncbi.nlm.nih.gov/pubmed/27121779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/rheumatology/kew192
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