Maternal metabolic syndrome programs mitochondrial dysfunction via germline changes across three generations

Maternal obesity impairs offspring health, but the responsible mechanisms are not fully established. To address this question, we fed female mice a high-fat/high-sugar diet from before conception until weaning and then followed the outcomes in the next three generations of offspring, all fed a contr...

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Bibliographic Details
Published in:Cell Rep
Main Authors: Saben, Jessica L., Boudoures, Anna L., Asghar, Zeenat, Thompson, Alysha, Drury, Andrea, Zhang, Wendy, Chi, Maggie, Cusumano, Andrew, Scheaffer, Suzanne, Moley, Kelle
Format: Artigo
Language:Inglês
Published: 2016
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4957639/
https://ncbi.nlm.nih.gov/pubmed/27320925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.05.065
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