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Maternal metabolic syndrome programs mitochondrial dysfunction via germline changes across three generations

Maternal obesity impairs offspring health, but the responsible mechanisms are not fully established. To address this question, we fed female mice a high-fat/high-sugar diet from before conception until weaning and then followed the outcomes in the next three generations of offspring, all fed a contr...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Saben, Jessica L., Boudoures, Anna L., Asghar, Zeenat, Thompson, Alysha, Drury, Andrea, Zhang, Wendy, Chi, Maggie, Cusumano, Andrew, Scheaffer, Suzanne, Moley, Kelle
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4957639/
https://ncbi.nlm.nih.gov/pubmed/27320925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.05.065
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