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Tunable recombinant protein expression in E. coli: enabler for continuous processing?

Tuning of transcription is a powerful process technological tool for efficient recombinant protein production in Escherichia coli. Many challenges such as product toxicity, formation of inclusion bodies, cell death, and metabolic burden are associated with non-suitable (too high or too low) levels o...

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Detalhes bibliográficos
Publicado no:Appl Microbiol Biotechnol
Main Authors: Marschall, Lukas, Sagmeister, Patrick, Herwig, Christoph
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4957632/
https://ncbi.nlm.nih.gov/pubmed/27170324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00253-016-7550-4
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