Disc cell senescence in intervertebral disc degeneration: Causes and molecular pathways

The accumulation of senescent disc cells in degenerative intervertebral disc (IVD) suggests the detrimental roles of cell senescence in the pathogenesis of intervertebral disc degeneration (IDD). Disc cell senescence decreased the number of functional cells in IVD. Moreover, the senescent disc cells...

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Bibliographic Details
Published in:Cell Cycle
Main Authors: Feng, Chencheng, Liu, Huan, Yang, Minghui, Zhang, Yang, Huang, Bo, Zhou, Yue
Format: Artigo
Language:Inglês
Published: Taylor & Francis 2016
Subjects:
Review
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4957599/
https://ncbi.nlm.nih.gov/pubmed/27192096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2016.1152433
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