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Quantitative assessment of chromosome instability induced through chemical disruption of mitotic progression

Most solid tumors are aneuploid, carrying an abnormal number of chromosomes, and they frequently missegregate whole chromosomes in a phenomenon termed chromosome instability (CIN). While CIN can be provoked through disruption of numerous mitotic pathways, it is not clear which of these mechanisms ar...

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Bibliografske podrobnosti
izdano v:Cell Cycle
Main Authors: Markossian, Sarine, Arnaoutov, Alexei, Saba, Nakhle S., Larionov, Vladimir, Dasso, Mary
Format: Artigo
Jezik:Inglês
Izdano: Taylor & Francis 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4957569/
https://ncbi.nlm.nih.gov/pubmed/27104376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2016.1175796
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