Galectin-3 Plays an Important Pro-inflammatory Role in the Induction Phase of Acute Colitis by Promoting Activation of NLRP3 Inflammasome and Production of IL-1β in Macrophages

BACKGROUND AND AIMS: Galectin-3 [Gal-3] is an endogenous lectin with a broad spectrum of immunoregulatory effects: it plays an important role in autoimmune/inflammatory and malignant diseases, but the precise role of Gal-3 in pathogenesis of ulcerative colitis is still unknown. METHODS: We used a mo...

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Detalhes bibliográficos
Publicado no:J Crohns Colitis
Main Authors: Simovic Markovic, Bojana, Nikolic, Aleksandar, Gazdic, Marina, Bojic, Sanja, Vucicevic, Ljubica, Kosic, Milica, Mitrovic, Slobodanka, Milosavljevic, Milos, Besra, Gurdyal, Trajkovic, Vladimir, Arsenijevic, Nebojsa, Lukic, Miodrag L., Volarevic, Vladislav
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4957458/
https://ncbi.nlm.nih.gov/pubmed/26786981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ecco-jcc/jjw013
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