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M1 Macrophages Activate Notch Signalling in Epithelial Cells: Relevance in Crohn’s Disease

BACKGROUND: The Notch signalling pathway plays an essential role in mucosal regeneration, which constitutes a key goal of Crohn’s disease (CD) treatment. Macrophages coordinate tissue repair and several phenotypes have been reported which differ in the expression of surface proteins, cytokines and h...

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Detalhes bibliográficos
Publicado no:J Crohns Colitis
Main Authors: Ortiz-Masiá, D., Cosín-Roger, J., Calatayud, S., Hernández, C., Alós, R., Hinojosa, J., Esplugues, J. V., Barrachina, M. D.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4957456/
https://ncbi.nlm.nih.gov/pubmed/26802079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ecco-jcc/jjw009
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