Progastrin Represses the Alternative Activation of Human Macrophages and Modulates Their Influence on Colon Cancer Epithelial Cells

Macrophage infiltration is a negative prognostic factor for most cancers but gastrointestinal tumors seem to be an exception. The effect of macrophages on cancer progression depends on their phenotype, which may vary between M1 (pro-inflammatory, defensive) to M2 (tolerogenic, pro-tumoral). Gastroin...

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Detalhes bibliográficos
Main Authors: Hernández, Carlos, Barrachina, María Dolores, Cosín-Roger, Jesús, Ortiz-Masiá, Dolores, Álvarez, Ángeles, Terrádez, Liria, Nicolau, María Jesús, Alós, Rafael, Esplugues, Juan Vicente, Calatayud, Sara
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4047028/
https://ncbi.nlm.nih.gov/pubmed/24901518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0098458
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