Serum IgG against Simian Virus 40 antigens are hampered by high levels of sHLA-G in patients affected by inflammatory neurological diseases, as multiple sclerosis

BACKGROUND: Many investigators detected the simian polyomavirus SV40 footprints in human brain tumors and neurologic diseases and recently it has been indicated that SV40 seems to be associated with multiple sclerosis (MS) disease. Interestingly, SV40 interacts with human leukocyte antigen (HLA) cla...

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Veröffentlicht in:J Transl Med
Hauptverfasser: Rizzo, Roberta, Pietrobon, Silvia, Mazzoni, Elisa, Bortolotti, Daria, Martini, Fernanda, Castellazzi, Massimiliano, Casetta, Ilaria, Fainardi, Enrico, Di Luca, Dario, Granieri, Enrico, Tognon, Mauro
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2016
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Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4957417/
https://ncbi.nlm.nih.gov/pubmed/27443345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-016-0981-y
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