Epstein-Barr virus-specific intrathecal oligoclonal IgG production in relapsing-remitting multiple sclerosis is limited to a subset of patients and is composed of low-affinity antibodies

BACKGROUND: The purpose of this study was to investigate intrathecal production and affinity distributions of Epstein-Barr virus (EBV)-specific antibodies in multiple sclerosis (MS) and controls. METHODS: Cerebrospinal fluid (CSF) and serum concentrations, quantitative intrathecal synthesis, oligocl...

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Veröffentlicht in:J Neuroinflammation
Hauptverfasser: Castellazzi, Massimiliano, Contini, Carlo, Tamborino, Carmine, Fasolo, Francesca, Roversi, Gloria, Seraceni, Silva, Rizzo, Roberta, Baldi, Eleonora, Tola, Maria Rosaria, Bellini, Tiziana, Granieri, Enrico, Fainardi, Enrico
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2014
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4232674/
https://ncbi.nlm.nih.gov/pubmed/25391491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-014-0188-1
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