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Cloned and expressed macrophage nitric oxide synthase contrasts with the brain enzyme.

Nitric oxide (NO) is a messenger molecule of macrophages, endothelial cells in blood vessels, and neurons. A neuronal form of NO synthase (NOS) has been previously cloned. We now report the molecular cloning of macrophage NOS. The macrophage enzyme displays 50% sequence identity to the neuronal enzy...

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Bibliographic Details
Main Authors: Lowenstein, C J, Glatt, C S, Bredt, D S, Snyder, S H
Format: Artigo
Language:Inglês
Published: 1992
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC49573/
https://ncbi.nlm.nih.gov/pubmed/1379716
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