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Cloned and expressed macrophage nitric oxide synthase contrasts with the brain enzyme.

Nitric oxide (NO) is a messenger molecule of macrophages, endothelial cells in blood vessels, and neurons. A neuronal form of NO synthase (NOS) has been previously cloned. We now report the molecular cloning of macrophage NOS. The macrophage enzyme displays 50% sequence identity to the neuronal enzy...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Lowenstein, C J, Glatt, C S, Bredt, D S, Snyder, S H
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1992
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC49573/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1379716/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.15.6711
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