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Dysfunctional epileptic neuronal circuits and dysmorphic dendritic spines are mitigated by platelet-activating factor receptor antagonism

Temporal lobe epilepsy or limbic epilepsy lacks effective therapies due to a void in understanding the cellular and molecular mechanisms that set in motion aberrant neuronal network formations during the course of limbic epileptogenesis (LE). Here we show in in vivo rodent models of LE that the phos...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Musto, Alberto E., Rosencrans, Robert F., Walker, Chelsey P., Bhattacharjee, Surjyadipta, Raulji, Chittalsinh M., Belayev, Ludmila, Fang, Zhide, Gordon, William C., Bazan, Nicolas G.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4957208/
https://ncbi.nlm.nih.gov/pubmed/27444269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep30298
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