Dysfunctional epileptic neuronal circuits and dysmorphic dendritic spines are mitigated by platelet-activating factor receptor antagonism

Temporal lobe epilepsy or limbic epilepsy lacks effective therapies due to a void in understanding the cellular and molecular mechanisms that set in motion aberrant neuronal network formations during the course of limbic epileptogenesis (LE). Here we show in in vivo rodent models of LE that the phos...

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Udgivet i:Sci Rep
Main Authors: Musto, Alberto E., Rosencrans, Robert F., Walker, Chelsey P., Bhattacharjee, Surjyadipta, Raulji, Chittalsinh M., Belayev, Ludmila, Fang, Zhide, Gordon, William C., Bazan, Nicolas G.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4957208/
https://ncbi.nlm.nih.gov/pubmed/27444269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep30298
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