1,2-Propanediol Dehydration in Roseburia inulinivorans: STRUCTURAL BASIS FOR SUBSTRATE AND ENANTIOMER SELECTIVITY

Glycyl radical enzymes (GREs) represent a diverse superfamily of enzymes that utilize a radical mechanism to catalyze difficult, but often essential, chemical reactions. In this work we present the first biochemical and structural data for a GRE-type diol dehydratase from the organism Roseburia inul...

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Veröffentlicht in:J Biol Chem
Hauptverfasser: LaMattina, Joseph W., Keul, Nicholas D., Reitzer, Pierre, Kapoor, Suraj, Galzerani, Felipe, Koch, Daniel J., Gouvea, Iuri E., Lanzilotta, William N.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2016
Schlagworte:
Protein Structure and Folding
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4957038/
https://ncbi.nlm.nih.gov/pubmed/27252380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.721142
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