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Serotonin biosynthesis as a predictive marker of serotonin pharmacodynamics and disease-induced dysregulation
The biogenic amine serotonin (5-HT) is a multi-faceted hormone that is synthesized from dietary tryptophan with the rate limiting step being catalyzed by the enzyme tryptophan hydroxylase (TPH). The therapeutic potential of peripheral 5-HT synthesis inhibitors has been demonstrated in a number of cl...
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| Publicado no: | Sci Rep |
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| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4956766/ https://ncbi.nlm.nih.gov/pubmed/27444653 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep30059 |
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