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Structural Insights into Arl1-Mediated Targeting of the Arf-GEF BIG1 to the trans-Golgi
The GTPase Arf1 is the major regulator of vesicle traffic at both the cis- and trans-Golgi. Arf1 is activated at the cis-Golgi by the guanine nucleotide exchange factor (GEF) GBF1 and at the trans-Golgi by the related GEF BIG1 or its paralog, BIG2. The trans-Golgi-specific targeting of BIG1 and BIG2...
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| Publicado no: | Cell Rep |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cell Press
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4956616/ https://ncbi.nlm.nih.gov/pubmed/27373159 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.06.022 |
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