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Importance of the evaluation of N-acetyltransferase enzyme activity prior to 5-aminosalicylic acid medication for ulcerative colitis
BACKGROUND: 5-aminosalicylic acid (5-ASA) is a classic anti-inflammatory drug for the treatment of ulcerative colitis. N-Acetyltransferase (NAT) enzymes convert 5-ASA to its metabolite N-acetyl-5-aminosalicylic acid (Ac-5-ASA) and it is unresolved whether 5-ASA or Ac-5-ASA is the effective therapeut...
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| Izdano u: | Inflamm Bowel Dis |
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| Glavni autori: | , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2016
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4956520/ https://ncbi.nlm.nih.gov/pubmed/27416043 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MIB.0000000000000823 |
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