Spinal microgliosis due to resident microglial proliferation is required for pain hypersensitivity after peripheral nerve injury

Peripheral nerve injury causes neuropathic pain accompanied by remarkable microgliosis in the spinal cord dorsal horn. However, it is still debated whether infiltrated monocytes contribute to injury-induced expansion of the microglial population. Here we found that spinal microgliosis predominantly...

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Veröffentlicht in:Cell Rep
Hauptverfasser: Gu, Nan, Peng, Jiyun, Murugan, Madhuvika, Wang, Xi, Eyo, Ukpong B., Sun, Dongming, Ren, Yi, DiCicco-Bloom, Emanuel, Young, Wise, Dong, Hailong, Wu, Long-Jun
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4956495/
https://ncbi.nlm.nih.gov/pubmed/27373153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.06.018
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