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Hypoxia Studies with Pimonidazole in vivo

Therapy-induced hypoxia drives changes in the tumor microenvironment that contribute to the poor response to therapy. Hypoxia is capable of driving the expression and/or activation of specific signaling cascades (e.g., c-Met, Axl, CTGF), the recruitment of tumor promoting immune cells, and the induc...

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Detalles Bibliográficos
Publicado en:Bio Protoc
Main Authors: Aguilera, Kristina Y., Brekken, Rolf A.
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4956402/
https://ncbi.nlm.nih.gov/pubmed/27453908
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