Interferon-gamma potentiates NMDA receptor signaling in spinal dorsal horn neurons via microglia–neuron interaction

BACKGROUND: Glia–neuron interactions play an important role in the development of neuropathic pain. Expression of the pro-inflammatory cytokne →cytokine Interferon-gamma (IFNγ) is upregulated in the dorsal horn after peripheral nerve injury, and intrathecal IFNγ administration induces mechanical all...

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Vydáno v:Mol Pain
Hlavní autoři: Sonekatsu, Mayumi, Taniguchi, Wataru, Yamanaka, Manabu, Nishio, Naoko, Tsutsui, Shunji, Yamada, Hiroshi, Yoshida, Munehito, Nakatsuka, Terumasa
Médium: Artigo
Jazyk:Inglês
Vydáno: SAGE Publications 2016
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4956380/
https://ncbi.nlm.nih.gov/pubmed/27094552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1744806916644927
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