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Efficacy Coefficients Determined Using Nail Permeability and Antifungal Activity in Keratin-Containing Media Are Useful for Predicting Clinical Efficacies of Topical Drugs for Onychomycosis

Onychomycosis is difficult to treat topically due to the deep location of the infection under the densely keratinized nail plate. In order to obtain an in vitro index that is relevant to the clinical efficacy of topical anti-onychomycosis drugs, we profiled five topical drugs: amorolfine, ciclopirox...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:PLoS One
Prif Awduron: Matsuda, Yoshiki, Sugiura, Keita, Hashimoto, Takashi, Ueda, Akane, Konno, Yoshihiro, Tatsumi, Yoshiyuki
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4956321/
https://ncbi.nlm.nih.gov/pubmed/27441843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0159661
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