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Comprehensive and differential long-term characterization of the alpha-galactosidase A deficient mouse model of Fabry disease focusing on the sensory system and pain development

BACKGROUND: Fabry disease is an X-linked lysosomal storage disorder due to impaired activity of alpha-galactosidase A with intracellular accumulation of globotriaosylceramide. Associated small fiber pathology leads to characteristic pain in Fabry disease. We systematically assessed sensory system, p...

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Vydáno v:Mol Pain
Hlavní autoři: Üçeyler, Nurcan, Biko, Lydia, Hose, Dorothea, Hofmann, Lukas, Sommer, Claudia
Médium: Artigo
Jazyk:Inglês
Vydáno: SAGE Publications 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4956180/
https://ncbi.nlm.nih.gov/pubmed/27145802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1744806916646379
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