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ATR- and ATM-Mediated DNA Damage Response Is Dependent on Excision Repair Assembly during G1 but Not in S Phase of Cell Cycle

Cell cycle checkpoint is mediated by ATR and ATM kinases, as a prompt early response to a variety of DNA insults, and culminates in a highly orchestrated signal transduction cascade. Previously, we defined the regulatory role of nucleotide excision repair (NER) factors, DDB2 and XPC, in checkpoint a...

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Bibliografiska uppgifter
I publikationen:PLoS One
Huvudupphovsmän: Ray, Alo, Blevins, Chessica, Wani, Gulzar, Wani, Altaf A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2016
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4956099/
https://ncbi.nlm.nih.gov/pubmed/27442013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0159344
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