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Kynurenine pathway dysfunction in the pathophysiology and treatment of depression: evidences from animal and human studies

Treatment-resistant depression affects up to 20% of individuals suffering from major depressive disorder (MDD). The medications currently available to treat depression, including serotonin re-uptake inhibitors (SSRIs), monoamine oxidase inhibitors (MAOIs) and tricyclic antidepressants (TCAs), fail t...

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Dettagli Bibliografici
Pubblicato in:J Psychiatr Res
Autori principali: Réus, Gislaine Z., Jansen, Karen, Titus, Stephanie, Carvalho, André F., Gabbay, Vilma, Quevedo, João
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4955923/
https://ncbi.nlm.nih.gov/pubmed/26028548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpsychires.2015.05.007
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