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Early changes in gene expression induced by blue light irradiation of A2E-laden retinal pigment epithelial cells

PURPOSE: Accumulation of bisretinoids as lipofuscin in retinal pigment epithelial (RPE) cells is implicated in the pathogenesis of some blinding diseases including age-related macular degeneration (AMD). To identify genes whose expression may change under conditions of bisretinoid accumulation, we i...

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Foilsithe in:Acta Ophthalmol
Main Authors: van der Burght, Barbro W., Hansen, Morten, Olsen, Jørgen, Zhou, Jilin, Wu, Yalin, Nissen, Mogens H., Sparrow, Janet R.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2013
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4955808/
https://ncbi.nlm.nih.gov/pubmed/23742627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/aos.12146
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