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Commensal microbiota has disparate effects on manifestations of polyglandular autoimmune inflammation

Polyglandular autoimmune inflammation accompanies Type 1 diabetes (T1D) in NOD mice affecting organs like thyroid and salivary glands. Whereas commensals are not required for T1D progression, germ-free (GF) mice had a very low degree of sialitis, which was restored by colonization with select microb...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Hansen, Camilla H.F., Yurkovetskiy, Leonid A., Chervonsky, Alexander V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4955756/
https://ncbi.nlm.nih.gov/pubmed/27324130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1502465
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