Gender bias in autoimmunity is influenced by microbiota

Gender bias and the role of sex hormones in autoimmune diseases are well established. In specific pathogen-free (SPF) non-obese diabetic (NOD) mice, females have 1.3–4.4 times higher incidence of Type 1 diabetes (T1D). Germ-free (GF) mice lost the gender bias (female/male ratio 1.1–1.2). Gut microbi...

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Detalhes bibliográficos
Main Authors: Yurkovetskiy, Leonid, Burrows, Michael, Khan, Aly A., Graham, Laura, Volchkov, Pavel, Becker, Lev, Antonopoulos, Dionysios, Umesaki, Yoshinori, Chervonsky, Alexander V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3822899/
https://ncbi.nlm.nih.gov/pubmed/23973225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2013.08.013
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