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The transcriptional repressor Hes1 attenuates inflammation via regulating transcriptional elongation

Most of the known regulatory mechanisms that curb inflammatory gene expression target pre-transcription initiation steps and evidence for regulation of inflammatory gene expression post initiation remains scarce. Here we show that transcription repressor hairy and enhancer of split 1 (Hes1) suppress...

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Detalhes bibliográficos
Publicado no:Nat Immunol
Main Authors: Shang, Yingli, Coppo, Maddalena, He, Teng, Ning, Fei, Yu, Li, Kang, Lan, Zhang, Bin, Ju, Chanyang, Qiao, Yu, Zhao, Baohong, Gessler, Manfred, Rogatsky, Inez, Hu, Xiaoyu
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4955730/
https://ncbi.nlm.nih.gov/pubmed/27322654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.3486
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