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Specialized proteasome subunits play an essential role in thymic selection of CD8(+) T cells
The cells that stimulate positive selection express different specialized proteasome β-subunits than all other cells, including those involved in negative selection. Mice that lack all four specialized proteasome β-subunits, and therefore express only constitutive proteasomes in all cells, had a pro...
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| Publicado no: | Nat Immunol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4955723/ https://ncbi.nlm.nih.gov/pubmed/27294792 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.3480 |
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