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The “lnc” between 3D Chromatin Structure and X Chromosome Inactivation

The long non-coding RNA Xist directs a remarkable instance of developmentally regulated, epigenetic change known as X Chromosome Inactivation (XCI). By spreading in cis across the X chromosome from which it is expressed, Xist RNA facilities the creation of a heritably silent, heterochromatic nuclear...

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Détails bibliographiques
Publié dans:Semin Cell Dev Biol
Auteurs principaux: Pandya-Jones, Amy, Plath, Kathrin
Format: Artigo
Langue:Inglês
Publié: 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4955722/
https://ncbi.nlm.nih.gov/pubmed/27062886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcdb.2016.04.002
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