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A Worldwide Map of Plasmodium falciparum K13-Propeller Polymorphisms
BACKGROUND: Recent gains in reducing the global burden of malaria are threatened by the emergence of Plasmodium falciparum resistance to artemisinins. The discovery that mutations in portions of a P. falciparum gene encoding kelch (K13)–propeller domains are the major determinant of resistance has p...
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| Publicado no: | N Engl J Med |
|---|---|
| Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4955562/ https://ncbi.nlm.nih.gov/pubmed/27332904 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa1513137 |
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