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Virtual screening and experimental validation of novel histone deacetylase inhibitors

BACKGROUND: Histone deacetylases (HDACs) are promising therapeutic targets for the treatment of cancer, diabetes and other human diseases. HDAC inhibitors, as a new class of potential therapeutic agents, have attracted a great deal of interest for both research and clinical applications. Increasing...

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Detalhes bibliográficos
Publicado no:BMC Pharmacol Toxicol
Main Authors: Huang, Yan-xin, Zhao, Jian, Song, Qiu-hang, Zheng, Li-hua, Fan, Cong, Liu, Ting-ting, Bao, Yong-li, Sun, Lu-guo, Zhang, Li-biao, Li, Yu-xin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4955146/
https://ncbi.nlm.nih.gov/pubmed/27443303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40360-016-0075-8
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