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Virtual screening and experimental validation of novel histone deacetylase inhibitors
BACKGROUND: Histone deacetylases (HDACs) are promising therapeutic targets for the treatment of cancer, diabetes and other human diseases. HDAC inhibitors, as a new class of potential therapeutic agents, have attracted a great deal of interest for both research and clinical applications. Increasing...
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Publicado no: | BMC Pharmacol Toxicol |
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Main Authors: | , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
BioMed Central
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4955146/ https://ncbi.nlm.nih.gov/pubmed/27443303 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40360-016-0075-8 |
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