Prognostic significance of FOXM1 expression and antitumor effect of FOXM1 inhibition in synovial sarcomas

BACKGROUND: Synovial sarcoma (SS) is a soft tissue sarcoma of unknown histogenesis. Most metastatic or unresectable cases are incurable. Novel antitumor agents and precise prognostication are needed for SS patients. The protein forkhead box M1 (FOXM1), which belongs to the FOX family of transcriptio...

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Published in:BMC Cancer
Main Authors: Maekawa, Akira, Kohashi, Kenichi, Kuda, Masaaki, Iura, Kunio, Ishii, Takeaki, Endo, Makoto, Nakatsura, Tetsuya, Iwamoto, Yukihide, Oda, Yoshinao
Format: Artigo
Language:Inglês
Published: BioMed Central 2016
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4955131/
https://ncbi.nlm.nih.gov/pubmed/27439614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-016-2542-4
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