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Prognostic significance of FOXM1 expression and antitumor effect of FOXM1 inhibition in synovial sarcomas

BACKGROUND: Synovial sarcoma (SS) is a soft tissue sarcoma of unknown histogenesis. Most metastatic or unresectable cases are incurable. Novel antitumor agents and precise prognostication are needed for SS patients. The protein forkhead box M1 (FOXM1), which belongs to the FOX family of transcriptio...

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Vydáno v:BMC Cancer
Hlavní autoři: Maekawa, Akira, Kohashi, Kenichi, Kuda, Masaaki, Iura, Kunio, Ishii, Takeaki, Endo, Makoto, Nakatsura, Tetsuya, Iwamoto, Yukihide, Oda, Yoshinao
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4955131/
https://ncbi.nlm.nih.gov/pubmed/27439614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-016-2542-4
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