Profile of MMP and TIMP Expression in Human Pancreatic Stellate Cells: Regulation by IL-1α and TGFβ and Implications for Migration of Pancreatic Cancer Cells()

Pancreatic ductal adenocarcinoma is characterized by a prominent fibroinflammatory stroma with both tumor-promoting and tumor-suppressive functions. The pancreatic stellate cell (PSC) is the major cellular stromal component and the main producer of extracellular matrix proteins, including collagens,...

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Publicat a:Neoplasia
Autors principals: Tjomsland, Vegard, Pomianowska, Eva, Aasrum, Monica, Sandnes, Dagny, Verbeke, Caroline Sophie, Gladhaug, Ivar Prydz
Format: Artigo
Idioma:Inglês
Publicat: Neoplasia Press 2016
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Original article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4954934/
https://ncbi.nlm.nih.gov/pubmed/27435927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2016.06.003
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