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PF-05231023, a long-acting FGF21 analogue, decreases body weight by reduction of food intake in non-human primates

PF-05231023, a long-acting FGF21 analogue, is a promising potential pharmacotherapy for the treatment of obesity and associated comorbidities. Previous studies have shown the potential of FGF21 and FGF21-like compounds to decrease body weight in mice, non-human primates, and humans; the precise mech...

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Bibliografiske detaljer
Udgivet i:J Pharmacokinet Pharmacodyn
Main Authors: Thompson, W. Clayton, Zhou, Yingjiang, Talukdar, Saswata, Musante, Cynthia J.
Format: Artigo
Sprog:Inglês
Udgivet: Springer US 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4954843/
https://ncbi.nlm.nih.gov/pubmed/27405817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10928-016-9481-1
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