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A Review of the Giant Protein Titin in Clinical Molecular Diagnostics of Cardiomyopathies
Titin (TTN) is known as the largest sarcomeric protein that resides within the heart muscle. Due to alternative splicing of TTN, the heart expresses two major isoforms (N2B and N2BA) that incorporate four distinct regions termed the Z-line, I-band, A-band, and M-line. Next-generation sequencing allo...
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| Publicado no: | Front Cardiovasc Med |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4954824/ https://ncbi.nlm.nih.gov/pubmed/27493940 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcvm.2016.00021 |
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