Efficient Inhibition of HIV Replication in the Gastrointestinal and Female Reproductive Tracts of Humanized BLT Mice by EFdA

BACKGROUND: The nucleoside reverse transcriptase inhibitor (NRTI) 4'-ethynyl-2-fluoro-2'-deoxyadenosine (EFdA) in preclinical development exhibits improved safety and antiviral activity profiles with minimal drug resistance compared to approved NRTIs. However, the systemic antiviral effica...

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Bibliografiska uppgifter
I publikationen:PLoS One
Huvudupphovsmän: Shanmugasundaram, Uma, Kovarova, Martina, Ho, Phong T., Schramm, Nathaniel, Wahl, Angela, Parniak, Michael A., Garcia, J. Victor
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2016
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4954669/
https://ncbi.nlm.nih.gov/pubmed/27438728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0159517
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