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Learning to Predict miRNA-mRNA Interactions from AGO CLIP Sequencing and CLASH Data

Recent technologies like AGO CLIP sequencing and CLASH enable direct transcriptome-wide identification of AGO binding and miRNA target sites, but the most widely used miRNA target prediction algorithms do not exploit these data. Here we use discriminative learning on AGO CLIP and CLASH interactions...

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Dades bibliogràfiques
Publicat a:PLoS Comput Biol
Autors principals: Lu, Yuheng, Leslie, Christina S.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4954643/
https://ncbi.nlm.nih.gov/pubmed/27438777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1005026
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