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Mapping small-effect and linked quantitative trait loci for complex traits in backcross or DH populations via a multi-locus GWAS methodology

Composite interval mapping (CIM) is the most widely-used method in linkage analysis. Its main feature is the ability to control genomic background effects via inclusion of co-factors in its genetic model. However, the result often depends on how the co-factors are selected, especially for small-effe...

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Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Wang, Shi-Bo, Wen, Yang-Jun, Ren, Wen-Long, Ni, Yuan-Li, Zhang, Jin, Feng, Jian-Ying, Zhang, Yuan-Ming
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4951730/
https://ncbi.nlm.nih.gov/pubmed/27435756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep29951
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